By Ahmed Ammar MD., Ph.D. (auth.), Assoc. Prof. Dr. Christer Lindquist, Assoc. Prof. Dr. Douglas Kondziolka, Assoc. Prof. Dr. Jay S. Loeffler (eds.)
Radiosurgery is a speedily constructing kind of minimally invasive neurosurgery. chosen papers from the 1st assembly of the foreign Stereotactic Radiosurgery Society in Stockholm, June 1993, replicate present multidisciplinary techniques to tricky intracranial neurosurgical difficulties. Neurosurgeons, radiotherapists, oncologists, radiobiologists, physicists and representatives of numerous different scientific disciplines tell in regards to the state of the art of radiosurgical remedy of a large number of intracranial difficulties equivalent to arteriovenous malformations, pituitary and pineal tumors, vestibular schwannomas in addition to metastatic mind tumors and gliomas.
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Extra resources for Advances in Radiosurgery: Proceedings of the 1st Congress of the International Stereotactic Radiosurgery Society, Stockholm 1993
Backlund E-O, Ganz JC (1993) Pituitary adenomas: Gamma 2. 3. 4. 5. 6. 7. 8. Knife. In: Alexander E, Loeffler JS, Lunsford LD (eds) Stereotactic radiosurgery. McGraw Hill, New York, pp 167-173 Backlund E-O (1979) Stereotactic radiosurgery in intracranial tumours and vascular malformations. In: Krayenbiihl H et at (eds) Advances and technical standards in neurosurgery, Vol 6. Springer, Wien New York, pp 1-37 Ganz JC, Backlund E-O, Thorsen FA (1993) The effects of gamma knife surgery of pituitary adenomas on tumour growth and endocrinopathies.
38 who indicated that, in patients with single metastases, 41 % were less than or equal to 3 cm diameter, while 53% were greater than 3 cm diameter (6% were of unknown size). 5 cm 3 no hypoxic cells. If hypoxia exists, the required doses will be higher. The SHMT values summarized in Table 13 may be used to generate the level of dose used in single fraction to produce sufficient cell killing, and these doses are listed in Table 13 (D 3cm ' Gy). Only for sarcomas and small cell lung cancers would a dose of 20 Gy provide roughly sufficient cell killing for an oxic tumor of 3 cm diameter.
19. However, conventional fractionated external beam irradiation of the pituitary gland requires several years to control tumor growth and reduce hormone secretion, and almost all of patients develop hypopituitarism within 5 to 7 years after treatment 16. 29, especially those who have failed surgical resection. 15, with 70-90% of patients in remission 1-4 years after irradiation. 20-22; in these early efforts the majority of patients had tumor localization using pneumoencephalopathy alone. Stephanian et al.